The ultimate question to science must be “how did the universe come to be?”. After that, I think the central question is “How did we come to be?. How did life come to the earth, and how did life create us?”
Science has been working on these questions for a relatively short time. Remember that untill the late 19th. century, most people believed that the universe was static and unchanging. That the way things looked now, was they way they always had looked and always would look. Some scientists clung to a steady-state universe up untill the 1960’s.
The fifth miracle by Paul Davies examines the search for the origin and meaning of life. It is a thorough overview of the scientific theories that are currently being used to explain life on earth.
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